alphazeta

对07年6月ISSCR在澳大利亚的第五届会议上关于CSCs研究成果的评述
1）题录：
Rajasekhar VK, Dalerba P, Passegué E, Lagasse E, Najbauer J.
Stem Cells, Cancer, and Context Dependence.
Stem Cells. 2007 Oct 25;
PMID:17962698
2）推荐理由：重要的ISSCR会议，最新的CSCs研究成果，了解CSCs动态必看。
3）全文：

yjzhang

Annals of Surgical Oncology最新肿瘤干细胞综述

1）题录：
Xiong-Zhi Wu, PhD
Origin of Cancer Stem Cells: The Role of Self-Renewal and Differentiation.
Annals of Surgical Oncology, 2007 最新
2）推荐理由：最新的CSCs研究成果，新文共欣赏。
3）全文：

chersm

这篇综述是关于干细胞在组织再生和肿瘤中的新近研究，颇为全面xin

chersm

这篇综述是关于干细胞在组织再生和肿瘤中的新近研究，颇为全面

goldideas

杂志全名及年卷： Annu Rev Pathol. 2007 Feb 28;2:175-189
文题： Cancer Stem Cells: At the Headwaters of Tumor Development
作者：Ward RJ, Dirks PB.
PMID： 18039097
推荐理由：最新的肿瘤干细胞综述

全文点击下载
http://www.stemness.net/bbs/attachment.php?aid=526

fleischer

太谢谢了，这么多好东西

heavenbird

质疑肿瘤干细胞的文章

heavenbird

质疑肿瘤干细胞的文章

heavenbird

又一篇不同观点的

okjiujiu99

1）题录：
Gao JX.
Cancer stem cells: the lessons from precancerous stem cells.
J Cell Mol Med. 2007 Dec 5 [Epub ahead of print]
PMID:18053092
2）推荐理由：癌前干细胞，干细胞研究的新进展。
3）全文：
Table of Contents
Introduction
Stem cells and cancer stem cells
Properties of stem cells
Cancer stem cell hypothesis
Development of precancerous and cancer stem cells
Origin of precancerous stem cells and cancer stem cells
Initiation and progression of precancerous stem cells
Clonal evolutionary relationship of precancerous stem cells to cancer stem cells
Characteristics of precancerous versus cancer stem cells
Are there demarcations between precancerous and cancer stem cells
Mainstay of precancerous stem cells: the potential for both benign and malignant differentiation
Conserved versus volatile phenotypes for precancerous and cancer stem cells
Genetic instability of precancerous and cancer stem cells
Subverted expression of embryonic and germline stem cell genes in precancerous stem cells
Contribution of precancerous and cancer stem cells to tumor malignancy

Can precancerous and cancer stem cells serve as the precursors of tumor stromal cells and tumor vasculogenic stem/progenitor cells (TVPCs)?
Does frequency of precancerous and cancer stem cells in tumors determine prognostic outcome of cancer?
Are precancerous and cancer stem cells associated with metastatic cancer?
Clonal evolution underlies the development of tumor-initiating cell (TIC) → precancerous stem cell (pCSC) → cancer stem cell (CSC)
Tumor initiation (TIC → pCSC): epigenetic alterations precede genetic mutations
Tumor progression (pCSC → CSC): additional dynamic genetic alterations
Clonal evolution and niche effect
Molecular pathways for the development of precancerous and cancer stem cells
Expression of embryonic, germline, and adult tissue stem cell-related genes in precancerous and cancer stem cells
Molecular pathways for self-renewal of precancerous and cancerous stem cells
Role of piwil2 in the development of precancerous and cancer stem cells
Do embryonic stem cell-related genes confer upon precancerous stem cells the capacity of transdifferentiation?
Experimental models for precancerous and cancerous stem cell research

Roadblock for discrimination of human precancerous and cancer stem cells
Approaches to establishing clonal precancerous and cancer stem cell lines
Phenotypic characterization and functional verification of precancerous and cancer stem cells
Clinical implications: early detection, prevention and treatment via targeting of precancerous and cancer stem cells
A novel strategy integrating early detection and prevention for the cure of cancer
Potential of piwil2 for early detection of cancer
Potential of precancerous and cancer stem cells as a target for immunoprevention
Potential of precancerous and cancer stem cells for the development of tumor vaccines
Concluding remark

d_enjoy2000

题录： 1: Ann Oncol. 2007 Oct;18(10):1605-19. Epub 2007 Mar 12.
Interplay of distinct growth factors during epithelial mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies.
作者：Mimeault M, Batra SK.
PMID: 17355951 [PubMed - in process]
推荐理由：针对肿瘤干细胞及其微环境的治疗策略作全面的综述，内容丰富

beconfident

太牛了～谢谢

sunny

我是新手,我也来推荐一篇.

littledrill

此文将端粒酶与肿瘤干细胞结合起来综述，以寻找肿瘤治疗靶标，角度较新，推荐阅读

qiujie1999_2004

Stem Cell Rev (2007) 3:1–6
Cancer and Stem Cell Signaling: A Guide to Preventive and Therapeutic Strategies for Cancer Stem Cells